1.Complication
The common complications include infection, cardiovascular complication, digestive complications, endocrine and metabolic abnormalities, Blood system complications, tumor, kidney disease recurrence.
2. The long-term survival rate is low
In clinical, the infection of kidney transplantation become the major puzzle for doctors and patients, especially cytomegalovirus infection. At the global level, 50% of kidney transplantation patients will be infected by cytomegalovirus, which can lead to several severe consequences such as increase the risk of acute or chronic rejection, cardiovascular disease, post transplantation diabetes mellitus, reduce the long-term survival rate.
Cardiovascular disease is the principal element of kidney transplantation lethal factor, about 50% of patients die of cardiovascular disease, which is mainly caused by post transplantation high blood pressure and hypercholesteremia.
Some experts have noted that about 20%~40% kidney transplantation patients will experience kidney function decrease, proteinuria, progressive anemia and shrink of the donor kidney, eventually turn into kidney failure within ten years.
3.Unsuitable for
The patients should not receive kidney transplantation, who have diseases include schizophrenia, metastatic tumors, chronic active hepatitis, liver cirrhosis, chronic obstructive pulmonary disease, bronchiectasia, disseminated tuberculosis, obstinate heart failure, clotting mechanism defect disease, polyarteritis nodosa, coccidioidomycosis, acquired immunodeficiency disease, Fabry's disease, primary hyperoxaluria.
4. Transplant reaction is hard to avoid
Kidney transplantation reaction is a kind of immunoreaction, which means that the patient’s immune system reject the allogenic antigen of donor kidney. In clinical, kidney transplantation rejection can be divided into hyperacute rejection, accelerated rejection, acute rejection and chronic rejection.
5. Patients need to take anti-rejection drugs for all their life
Transplant reaction is the common problem for kidney transplantation patients. Though anti-rejection drugs can improve the short period survival rate of transplantation, it have little effect for chronic reaction, which can lead to the loss of kidney function and the patients need dialysis again. The long-term using of anti-rejection drugs can drop the body's immune function, giving rise to infection.
6. The high cost of transplant
Patients need to pay for not only the transplant expense, but also the anti-rejection drugs.
By accounting for these factors, we can see that the kidney transplantation has huge risks. Is there have any other method to treat ESRD? The patients can receive the combine traditional Chinese and western medicine therapy to alleviate symptoms and restore body function gradually. More details please refer to “5C International Renal Health Restoring”
