1. Infection
Infection is the common complication and the main reasons that cause death. According to the statistics of International Study of Kidney Disease in Children in 1984, there are 70 percent of all nephritic syndrome deaths occur in infected children.
2. High coagulation state and thromboembolic complications
The children with nephritic syndrome will experience the increase of fibrinogen, blood platelet and anti-hemophilic factor VIII,V as well as the decrease of ATIII and the activity of the plasma fibrinolytic enzyme, these conditions will lead to high coagulation state and thromboembolic complications.
3. Metabolic disorder of calcium and vitamin D
The children with nephritic syndrome loss vitamin D binding protein through urine, the lack of vitamin D will affect the calcium absorb, leading to hyperparathyroidism.
4. Hypovolemia
The low plasma albumin and the decrease of plasma colloid osmotic pressure will cause hypovolemia in nephritic syndrome children.
5. Acute renal impairment
It is common that the nephritic syndrome children get mild nitrogen qualitative hematic disease, and they may experience acute renal impairment probably.
6. Renal tubular dysfunction
Renal tubular dysfunction can be represented as glycosuria, aminoaciduria, loss of potassium phosphate in the urine and lack of concentration function.
7. Atherosclerosis
Atherosclerosis can present in children with hyperlipidemia, once it happened, the child will experience chest distress, stenocardia, electrocardiogram changes, even death.
8. Neurological symptoms
Children with nephritic syndrome may have some neurological symptoms include headache, tic and visual impairment, these symptoms might result from hypertensive encephalopathy, encephaledema, dilutional hyponatremia, hypocalcemia, hypomagnesemia, etc.