Can IgA nephropathy patients have pregnancy? This is a question bothers the
female patients and their families most. Actually, we completely understand
their thinkings and concerns. Also, I think it is also very clear in their mind
that there are many risks for not only themselves, but also for the fetus.
There were some investigations showing that for most of the patients,
pregnancy is not a tough issue unless they have uncontrollable high blood
pressure and low GFR than 70ml/min.
However, we still think that only when patients meet the following conditions
can they think about pregnancy.
First, those who had stopped medication for more than three years after
treatment and there isn’t relapse during the three years can consider about
pregnancy. However, if there is any sign implying relapse of the disease, they
would better stop pregnancy immediately. And those with over 7 months pregnancy
can do C-section.
Second, if IgA happens during the pregnancy, which is due to overload of
kidney, patients can take some medicine following doctor’s instructions to
relieve the symptoms, which, after delivery can recover naturally. Usually, this
mainly refers to swelling due to pregnancy. And those whose clinical symptom is
hematuria are at high risk to have high blood pressure. And once they are
pregnant, they should check regularly and be very careful with their body.
Third, another condition is that patients’ condition is not stable and the
disease is active. Generally speaking, patients are not allowed to have
pregnancy, because IgA nephropathy is a kind of immune disease, and steroids are
usually applied to stabilize their condition, yet large-dose of steroids can
lead to hormone disturbance inside patient’s body, which also can lead to
malformation of fetus.
In one word, patient’s condition differs from each other and we can not make
conclusion without knowing patient’s specific condition. Beside, patients should
also be very cautious with pregnancy too in order to prevent unexpected loss or
death.