IgA nephropathy is an independent clinical pathological syndrome, which can
be shown as glomerular nephritis. IgA nephropathy is one of the main causes of
ESRD. The common kidney damage due to IgA nephropathy in children are as
below:
1. Paroxysmal gross hematuria
The IgA nephropathy patients will develop gross hematuria after they have got
various respiratory tract infections, so it can also be called as pharyngitis
synchronous blood urine. Some patients are usually accompanied with abdominal
pain who can be diagnosed with urinary stone or appendicitis. The abdominal pain
is the performance of systematic small vasculitis lesions, which may be related
with small artery inflammatory lesions in ureter and gastrointestinal
mucosa.
2. Nephrotic syndrome
Part of the patients will develop high blood pressure and blood urine. The
prognosis of patients with glomerular sclerosis and intrarenal vascular
sclerosis is poor. Patients with microscopic hematuria and asymptomatic mild
swelling will be diagnosed as glomerular nephritis easily, which should be
confirmed diagnosis by renal biopsy.
3. Simple proteinuria
4. Rapid-progressed nephritis
The condition is unusual, patients will experience continuous gross
hematuria, massive proteinuria, heart and brain affected, renal function rapid
deterioration.
Thus the child with IgA nephropathy should seek a proper treatment as soon as
possible to prevent further damage of kidney.
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