What is benign arteriolar nephrosclerosis

Benign arteriolar nephrosclerosis is a kidney complication of hypertension, it has become the second disease which can progress to end-stage renal failure in the western countries, the incidence in China is also increasing day by day.

Generally, the pathological examination of kidney can be found to have small artery lesions if benign hypertension has sustained 5~10 years. Clinical symptoms of this disease appeared later than pathological changes, usually 10~15 years later after hypertension occur, while old people, patients with hyperlipemia or hyperuricemia may occur earlier. Because the renal tubules are sensitive to ischemia, the earliest clinical symptoms are often night urination.
There is protein can be examined in the urine routine test when the glomerular ischemic lesions occur, and mildly abnormal also can be found in the sediment microscopy(a small amount of red blood cells and granular casts). With the progression of the disease, patients will suffer from renal failure, serum creatinine increasing, until develop into chronic renal failure. Benign hypertension often cause damage to other target organs except the damage to kidney, patients will often be accompanied by a hypertensive retinopathy(arteriosclerosis, bleeding and leakage of retina), and some cerebrovascular complications of hypertension.
In conclusion, reducing the blood pressure to normal value is the key to prevent benign arteriolar nephrosclerosis, patients with hypertension should take treatment as early as possible to reduce blood pressure.

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What manifestations will appear in the skin when someone get diabetic nephropathy？

Diabetic nephropathy is a common complication of diabetes and one of the manifestations of diabetes systemic microvascular lesions, it is characterized by proteinuria, progressive renal damage, hypertension and edema in clinic. However, it will appear to have severe renal failure when it reaches an advanced stage. Diabetic nephropathy is also one of the main causes which can lead to death in diabetic patients.

If someone get diabetic nephropathy, the skin will show differences at the first time. What manifestations will appear in the skin when someone get diabetic nephropathy?
1. The neck folliculitis. For patients with diabetic nephropathy, many will appear an inflammation like pus heat rash in the posterior neck, which may cause patients feel a sense of tenderness and tend to develop boil or cellulitis. The skin will heal after discharging the pus, but it may relapse in the near future.
2. Erythema on the skin. Such symptoms are like burn blisters which have thin wall, contain transparent slurry and have no glow around the bubbles. Normally erythema grow on the back or bottom edge of the fingers, toes, hand and foot, it appear either single or multiple and heal in a few weeks, but will relapse again and again.
3. Foot gangrene. Patients with diabetic nephropathy can experience foot pain, not be able to feel temperature, dry and crack, tend to develop ulcer, the fester, necrosis or even occurred perforation and it is difficult to heal.
4. Abnormal sweating. Patients often sweat a lot for no apparent reason, and more in upper limbs or trunk. Some patients even have the symptom of dripping sweat.
5. Skin itch. Some diabetic nephropathy patients will experience the skin desquamation due to the desiccation systemically or locally.

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How should people who want to protect kidney eat?

Many people no matter whether have kidney disease, often ask questions like “how to eat can keep healthy” . Actually, for many people, in addition to indispensable medication, correct and reasonable dietary habits are also especially important. Next let’s discuss what dietary guidelines we should follow as to the protection of the kidney.

In terms of keeping kidney healthy, we should first pay attention to nourishing essence, which emphasis on solid essence and preventing its loss. In order to achieve such a goal, you can eat more food that contain tonic substance, we often call them “black food” like black beans, black rice, black sesame seed, walnut, etc., and of course some Chinese medicinal food is also a good choice. What also important is to catch the best time to protect your kidney.
We all know that protecting kidney should start from the scratch, and habits in the daily life are rich in varying kinds of common sense for protecting kidney. Such as the daily drinking, we should drink water not wit until we are very thirsty and should get into the habit of drinking all the time. Water quantity deficiency can lead to shortage of the body, serious deficiency may even cause dehydration, and of course this is a risk for kidney or even the whole body. In addition, limiting salt intake strictly is also helpful to protect kidney. Because excessive salt intake can increase the kidney burden or cause too much salt accumulating in the body which all damages to kidney.
We should also prevent excessive intake of purines, eat less food contain high purine as far as possible, such as meat, aquatic products, yeast powder, wine and chicken powder,etc. Because too much purine intake can cause uric acid in the body elevating.
If you want to know more about the diet that can help you keep healthy, you can consult with our specialists online.

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Can patients with chronic nephritis be pregnant

Chronic nephritis is also called chronic glomerular nephritis,its clinical manifestations are proteinuria,edema and high blood pressure. It has longer duration and merging pregnancy are not uncommon.pregnancy can increase the burden of kidney and accordingly cause the symptoms mentioned above.

According to the varying degrees of nephritis, it also has different effects on the development of fetus. For patients have both chronic nephritis and high blood pressure often accompanied by placental function decline and insufficient supply of fetal blood. So people of this group should not be pregnant, because about 75% of these people will be complicated by severe pih high blood syndrome and stillbirth rate is extremely high.
Besides, patients whose renal function does not restore normal together with protein quantity, blood urea nitrogen and creatinine increasing, need to prevent renal failure appear. Thus patients are also not suitable to be pregnant. They should take induced abortion if it is early pregnancy.
However, if the chronic nephritis patients has basically normal renal function as well as only a small amount of urine protein and has a period of stability, then they can be pregnant, but should have a good rest and compensate enough nutrition like food contain high quality protein and vitamin. In addition, increasing the body resistance and avoiding all kinds of infections also do good for the recovery.
Clinical experience has proved that pregnant can aggravate the progression of nephritis and shorten the life span of patients.
If you want to learn more about chronic nephropathy, you can also ask our specialists online, they will give you satisfying answers.

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Modern medical treatment of IGA nephropathy

IGA nephropathy is the most common primary chronic glomerular disease, and its clinical manifestations are mainly protein urine or blood urine accompanied with protein urine. Here i will introduce some modern medical treatments of IGA nephropathy.

1. Adjust living habits. Especially in allusion to the individuals who have bad living habits, they should particularly change their bad habits and try their best to form new good living habits. Such as losing weight, giving up smoking, low-salt and low-fat diet, taking some aerobic exercise, etc.
2. Prevent infections. The best way to prevent infections is to boost resistance and avoid catching cold. If someone once get infected, he must get it controlled actively and thoroughly. If patients also have recurrent tonsillitis or certain blood urine concerned with tonsil infection, removing of the tonsils is suggested. Retrospective studies suggest that the tonsil excision is good for patients with mild-to-moderate IGA nephropathy.
3. Prevent drug use of ischemic and renal toxicity. The main measure is to ensure sufficient supply of blood so that we can avoid dehydration and severe hypotension. Reducing the use of renal toxicity drugs to maintain enough urine output is also helpful.
4. Other support therapy. Including the anticoagulation and antiplatelet aggregation, regulating blood lipid, traditional Chinese medicine, etc.
According to the above factors, we can conclude that the modern medical treatments of IGA nephropathy are some good living habits in the daily life. If you want to know more about IGA nephropathy and its treatments, you can contact our specialists online to acquire more information.

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What are the differences between lupus and ordinary skin disease?

Lupus is a disease that has a high morbidity and its damage to human body usually firstly embodies in the surface of the skin. So many people mistake lupus as ordinary skin disease and see the doctors in dermatological department.

In the first, skin disease is due to internal and external factors which can lead to changes of its morphology, structure and function, finally it will produce pathological process and varying kinds of clinical manifestations. While systemic lupus erythematosus is a systemic immune disease with multiple damages and a variety of autoantibodies, besides erythema on the skin, it also has the symptoms of low fever, renal involvement, photoresponse and pain in the joints of the limbs.
In the second place, patient’s skin with erythema mainly spread in the shape of butterfly, while ordinary skin disease have different manifestations depend on different categories. For example, damage to the skin of urticaria patients is mainly caused by allergy, and together with red rash that will disappear after allergic reaction fade out. On the other hand, the rash caused by lupus has dark color and will not disappear easily.
In the last, treatments are different between ordinary skin disease and lupus: ordinary skin disease can be treated by topical creams and some oral drugs, while hormonotherapy and immunotherapy is needed to treat lupus. What’s worse, there is no good way to prevent this kind of disease except to protest it by daily tonic.
Above all, if you find any symptoms related to lupus, you should attach great importance on it and take treatments as soon as possible. You can also ask our specialists online to learn about more information.

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How does hyperuricemia cause damage to kidneys

Hyperuricemia and gout are two different names for one disease. Gout is a disease caused by a group of purine metabolic disorders, in clinic, it is characterized by hyperuricemia and some complications which is due to hyperuricemia, like the relapse of acute gout arthritis, tophus deposit and chronic arthritis or joint deformity due to tophus, all of which often do harm to kidneys and lead to chronic interstitial nephritis and uric acid stone.

Almost one third of the patients who have long-term gout have kidney damage and it is characterized by the following three forms:
1. Gouty nephropathy. Urate crystal deposition in the kidney tissues can cause interstitial nephritis, simply in the form of proteinuria and microscopic hematuria in the early stage, so it is easy to be ignored. However, with the progression of disease, proteinuria become sustainable. The impairment of concentrating function in kidney lead to a serious of phenomena such as nocturia increasing and low proportion of urine. Eventually, patients will convert to uremia from chronic azotemia.
2. Acute renal failure. This is because large amounts of uric acid crystals widely block the cavity of renal tubular, thus causing obstruction of urine stream .
3. Lithangiuria. About 20%-25% of primary gout patients have the complications of urinary stones related to high uric acid, part of the patients have kidney stone that occurs earlier than arthritis. While patients with secondary hyperuricemia have higher incidence in allusion to lithangiuria. Kidney stones like fine sediment can be excreted in the urine without any symptoms, but patients with larger stones often have renal colic, hematuresis and urinary tract infections.

With regard to the nursing of hyperuricemia, patients should attach great importance to develop good habits in the daily life.
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