Which factors are associated with prognosis of chronic nephritis

Chronic glomerulonephritis will develop into renal failure after years unhealed, but the rate of progress come different in different people. We can not cure this disease fundamentally at present, while if we have the ability to prolong their renal function for years or decades, provide their chances to live and work normally, it is not only highly beneficial for patients and their families, but also for the society. Accordingly, those factors connected with progressing speed turn into focus to people. Here are some factors that already known.

1. Pathological factors. Different pathological change, different prognosis. For example, compared to severe mesangial proliferative glomerulonephritis and membrano proliferative glomerulonephritis, prognosis of simply mild mesangial proliferative glomerulonephritis is better. 50% Membrano proliferative glomerulonephritis develop renal failure in 10 years, chronic renal disease generally progress slowly and have good prognosis, few develop renal failure in 5 years, while focal segmental glomerulosclerosis has poor prognosis and usually develop into uremia in 10 to 20 years. In addition, other pathological factors affecting prognosis are: the crescent, the poorer prognosis is; patients with obvious or severe lesions on vessels inside kidneys like fibrinoid necrosis of small arteries have poor prognosis; patients with interstitial fibrosis and tubular atrophy have poor prognosis.
2. Clinical factors. ① patients have history of hemolytic streptococcus infection before have better prognosis;② who do not have other clinical symptoms except proteinuria or hematuria have better prognosis; ③ who have severe high blood pressure or high blood pressure progressing rapidly have poor prognosis, while patients can control the high blood pressure by medicines have better prognosis; ④ patients with little urine protein volume after treatment have better prognosis than those who have more or normal urine protein volume; ⑤ who with obvious anemia and edema have poor prognosis.
If you have any questions about kidney disease, you can believe that Beijing United-tech Nephrology Specialist Hospital is the best choice. And you can also contact us online.

Read more about: Why dose nephritis attack repeatedly?

Common causes of uremia

Uremia has a high incidence in our daily life and pose dramatically danger to our life. If someone reaches the stage of uremia, he or she is likely to confront great challenges both in physical function and mental health. So all the people should attach much importance on uremia in order to detect it early and treat it timely. In order to grasp it completely, we should find out common causes of uremia. Followings are some causes you can refer to.

1. Primary glomerulonephritis: if nephritis like membranoproliferative glomerulonephritis, rapidly progressing nephritis, membraneous nephritis and focal glomeruloscerosis are left untreated for a long time, they are likely to develop uremia.
2. Secondary glomerulonephritis: henoch-schonlein purpura nephritis, systematic lupus erythenlatosus nephritis, hypertension nephritis and diabetic nephropathy will step in uremia in the long run, because they can damage kidneys to varying degree.
3. Congenital and hereditary kidney disease: polycystic kidney, hereditary nephritis and all kinds of congenital renal tubular dysfunction can lead to uremia occur because of the impairment to kidneys’ ability to filter waste products.
4. Infectious disease: chronic pyelonephritis and nephrotuberculosis may also lead to occurrence of uremia, because such disease may affect other organs surround kidney and so as to the overall body.
5. Urinary tract blocked: kidney stone, bilateral ureteral obstruction, and narrow urinary tract will lead to waste products retaining in blood, increase burden of kidney, such condition will finally develop into uremia.
6. Other factors: some types of drug, heavy metal and keep on diet to lose weight all have great chance to induce uremia.
In general, no matter what the cause is, patients should observe what doctors instruct and take treatments as soon as possible in order to seize the best opportunity to protect kidneys.

Read more about:What should uremia patients do to get rid of dialysis

Is lipid-lowering medicine useful to kidney disease

Hyperlipidemia is closely associated with kidney disease, it is a common clinical manifestation of a lot of primary or secondary kidney disease (CKD), at the same time itself is involved in the occurrence and development of kidney disease.

Hyperlipidemia not only increase the incidence of cardiovascular disease, but also accelerate the progress of kidney disease, so the lipid-lowering therapy has certain protective effect to kidney. Large numbers of studies recently have shown that statins have a number of roles except lipid-lowering,including anti-inflammatory, immunomodulatory and directly inhibit mesangial cell proliferation and mesangial matrix increase, which with no doubt is of great significance to slow down the progress of kidney disease. It is well recognised that hyperlipidemia is the third major factor besides high blood pressure and albuminuria, which can promote the progression of kidney disease.
Nephrotic syndrome, diabetes kidney disease and end-stage renal disease patients often have lipid metabolic abnormalities involved, the latter not only cause arteriosclerosis, promote the kidney disease progress, but also can increase the incidence of cardiovascular complications. Lipid-lowering drugs like statins can significantly reduce the morbidity and mortality of cardiovascular events, whether with coronary or not, whatever basic lipid level is, statins can significantly reduce 23% of major vascular events. Which means statins is beneficial to improve the long-term prognosis of patients with ESRD. What’s more, statins is mainly excreted from liver and its renal excretion rate is less than 0.5%, which make statins relatively suitable for patients with kidney disease. In addition, studies have shown that it is safe and effective for patients with hypercholesterolemia nephrotic syndrome and hemodialysis to take statins constantly.
In view of all the above effects, statins can be widely used in many kinds of treatments in kidney disease, such as hyperplastic glomerulonephritis, ischemic renal disease, chronic kidney disease and polycystic kidney，etc.

Read more about : Early symptoms of diabetic nephropathy

What is the pathogenesis of diabetic nephropathy

The pathogenesis of diabetic nephropathy is very complicated, realizing it can be beneficial for people to keep their eyes on precautions and nursing in the daily life. Next we will introduce three main pathogenesis for people to refer to.

Genetic background. Diabetes is a polygenetic disease, no matter type 1 diabetes or type 2, there is a high relationship with individual’s genetic background whether people will get diabetic nephropathy or not. Someone who has blood glucose and blood pressure under control still suffer from diabetic nephropathy, while someone even though not control blood glucose and blood pressure well, they never experience diabetic nephropathy, which implies that individual’s different genetic backgrounds have different susceptibility to diabetic nephropathy. The incidence of diabetic nephropathy also depends on racial and ethnic, for instance, Asian people have a higher incidence of kidney disease than Caucasians.
1. Hemodynamic changes. Hemodynamic has already changed at the early stage of diabetic nephropathy, it plays an important role in the formation of diabetic nephropathy. Hemodynamic changes are mainly reflected in high perfusion, high filtration and high pressure within the glomerulus, all of these factors make glomerular work under the higher load, if this situation lasts long, glomerular will become fat, the open areas of vasoganglion will increase, basement membrane of blood vessel will become thicken and permeability increase, and then it will proceed to proteinuria and glomerular sclerosis which eventually promote the formation of diabetic nephropathy.
2. Metabolic disorder and insulin resistance. The most basic pathological change of diabetes is sugar metabolic problems, in this situation sugar in the body is higher than the normal range. Unfortunately, blood sugar and high glucose in the blood is toxic, called the“toxic sugar”, which is mainly because too much glucose may activate some substance which is harmful to kidney, it is thus that cause the diabetic nephropathy.
Read more about: Prevention measures to stop diabetic nephropathy from occurring

Clinical manifestations of chronic glomerular nephritis syndrome？

Chronic glomerulonephritis(chronic nephritis) syndrome refers to a group of similar clinical manifestations which have diverse etiology and different pathological form. It is important to learn about the clinical manifestations of chronic nephritis because of its hidden causes and mild symptoms that are easily to be overlooked at the early stage. Next i will list some common symptoms summarized by senior experts from Beijing United-Tech Nephrology Specialist Hospital.

1. Edema. In the whole course of the disease, most patients will appear to have different degree of edema, and many patients start with edema. Patients with mild edema only show edema on eyelid, faces after getting up in the morning, but it can subside after a few hours. But if you want to tell it from the edema caused by lack of sleep or staying up late, you should do a urine test to make sure whether it is nephritis.
2. Hypertension. Some patients go to see doctor because of hypertension, and urine test is the only necessary means to find out nephritis. For patients with chronic nephritis, hypertension will occur sooner or later. The increasing of blood pressure can be either persistent or intermittent, and it usually implies that the lesions have reached a certain degree. What’s more, the degree of blood pressure is closely associated with prognosis, generally the higher your blood pressure is, the longer it lasts, the more dangerous you will be and the worse of the prognosis.
3. The abnormal urine test. Chronic kidney disease patients’urine test will be surely abnormal, including the abnormally reasonable amount of urine and abnormal microscopic examination.The urine volume of the patients with edema will be reduced, and the more serious of the edema,the more urine he will reduced.Generally, if the patients do not have edema, his urine volume will be normal
4. Renal insufficiency. Chronic nephritis patients will have the symptoms of dizziness, insomnia and mental fatigue. Moreover, when patients’ renal function decreases, they will feel less of appetite, fatigue resistance, different degrees of anemia and other symptoms.
Above symptoms can either come together or alone, if patients can not have them under control, they are very likely to develop renal failure or even uremia. So patients should pay more attention to symptoms in the daily life.

Read more about: Nursing methods of nephrotic syndrome’s symptoms

What are the causes of hypertensive nephropathy?

Kidney disease can be divided into a lot of kinds, and high blood pressure is one of them. The damage to patients with this disease is pretty big, so everyone should take it seriously, especially the patients with this disease, must pay attention to the disease and learn more about the relevant knowledge of the disease. Then what are the causes of hypertensive nephropathy?

1. Long-term high blood pressure.
Hypertension is a serious disease, it will directly cause kidney pathological changes if not controlled for a long period, such as glomerular sclerosis and renal interstitial fibrosis which can lead to kidney function decline or finally develop into hypertensive nephropathy. Patients should take their blood pressure frequently and keep their blood pressure within the normal range and better take low salt, low fat food.
2. Unreasonable diet.
Many diseases have a direct relationship with diet, no matter the healthy group or disease group, regular and controlled diet is often suggested. Generally the onset of kidney disease is very slow, which need us require ourselves strictly like eating less food that are bad for kidney.
3. Bad living habits in the daily life.
Generally speaking, smoking and drinking are two factors most threatening to our body, it can also aggravate the high blood pressure and the damage to kidney function. Besides, emotion, staying up late, overtired and drug abuse all have chances causing hypertension nephropathy.
According to the causes above, everyone should pay more attention to their own living habits and diet, thus can not only do good to your whole body, but also make contribution to your kidney function.

Read more about:What caused the increased nocturia in hypertensive patients

How to identify whether the urine bubbles are caused by disease or not

The formation of urine bubbles is mainly related to the surface tension of the urine liquid. In general, the higher the liquid surface tension is, the easier it is to form bubbles. It is more likely to form bubbles due to the surface tension of the urine liquid increase when the urine components change, such as protein, mucus and organic substance increase. Usually, the occasional bubbles in the urine are more likely to be physiological but not pathological, which can get better itself. Next we will introduce some types of urine bubbles caused by disease.

1. Proteinuria. Abnormal elevation of protein in the urine is one of the most common causes, it is also an important clinical manifestation of various diseases, especially the kidney disease. All kinds of primary renal disease, such as various types of primary glomerular nephritis and secondary kidney damage, all can lead to proteinuria increase due to the kidney damage. While with regard to non-urinary system disease such as multiple myeloma, acute intravascular hemolysis, leukemia,etc, there are still some protein leak out in the urine although the renal function is normal.
2. Infection of urinary system. On the one hand, the increase of inflammatory secretions in the urinary tract can increase the surface tension of liquid, on the other hand, some infections caused by bacteria also can lead to bubbles in the urine. Common urinary tract infections, including urinary tract infection, cystitis, prostatitis,etc., are mostly accompanied by urinary frequency, urgency, urine pain and other symptoms.
3. Diabetes increase. Diabetic patients tend to produce bubbles in the urine because the elevated blood sugar and the urine sugar accordingly. In addition, eating a lot of carbon hydrates or inject large number of glucose also can lead to bubbles emerge.
4. Some other rare causes. Other causes for bubble urine also include bladder colon fistula,etc., but is very rare, which need special inspection to make a definite diagnosis.
Above all, for the repetitive bubble urine, it is necessary to see doctor timely and figure out what cause it on earth.
If you have any questions, you can contact us online.

Read more about: Affects of proteinuria on chronic kidney disease

What is benign arteriolar nephrosclerosis

Benign arteriolar nephrosclerosis is a kidney complication of hypertension, it has become the second disease which can progress to end-stage renal failure in the western countries, the incidence in China is also increasing day by day.

Generally, the pathological examination of kidney can be found to have small artery lesions if benign hypertension has sustained 5~10 years. Clinical symptoms of this disease appeared later than pathological changes, usually 10~15 years later after hypertension occur, while old people, patients with hyperlipemia or hyperuricemia may occur earlier. Because the renal tubules are sensitive to ischemia, the earliest clinical symptoms are often night urination.
There is protein can be examined in the urine routine test when the glomerular ischemic lesions occur, and mildly abnormal also can be found in the sediment microscopy(a small amount of red blood cells and granular casts). With the progression of the disease, patients will suffer from renal failure, serum creatinine increasing, until develop into chronic renal failure. Benign hypertension often cause damage to other target organs except the damage to kidney, patients will often be accompanied by a hypertensive retinopathy(arteriosclerosis, bleeding and leakage of retina), and some cerebrovascular complications of hypertension.
In conclusion, reducing the blood pressure to normal value is the key to prevent benign arteriolar nephrosclerosis, patients with hypertension should take treatment as early as possible to reduce blood pressure.

Read more about: What is FSGS

What manifestations will appear in the skin when someone get diabetic nephropathy？

Diabetic nephropathy is a common complication of diabetes and one of the manifestations of diabetes systemic microvascular lesions, it is characterized by proteinuria, progressive renal damage, hypertension and edema in clinic. However, it will appear to have severe renal failure when it reaches an advanced stage. Diabetic nephropathy is also one of the main causes which can lead to death in diabetic patients.

If someone get diabetic nephropathy, the skin will show differences at the first time. What manifestations will appear in the skin when someone get diabetic nephropathy?
1. The neck folliculitis. For patients with diabetic nephropathy, many will appear an inflammation like pus heat rash in the posterior neck, which may cause patients feel a sense of tenderness and tend to develop boil or cellulitis. The skin will heal after discharging the pus, but it may relapse in the near future.
2. Erythema on the skin. Such symptoms are like burn blisters which have thin wall, contain transparent slurry and have no glow around the bubbles. Normally erythema grow on the back or bottom edge of the fingers, toes, hand and foot, it appear either single or multiple and heal in a few weeks, but will relapse again and again.
3. Foot gangrene. Patients with diabetic nephropathy can experience foot pain, not be able to feel temperature, dry and crack, tend to develop ulcer, the fester, necrosis or even occurred perforation and it is difficult to heal.
4. Abnormal sweating. Patients often sweat a lot for no apparent reason, and more in upper limbs or trunk. Some patients even have the symptom of dripping sweat.
5. Skin itch. Some diabetic nephropathy patients will experience the skin desquamation due to the desiccation systemically or locally.

Read more about: Early symptoms of diabetic nephropathy

How should people who want to protect kidney eat?

Many people no matter whether have kidney disease, often ask questions like “how to eat can keep healthy” . Actually, for many people, in addition to indispensable medication, correct and reasonable dietary habits are also especially important. Next let’s discuss what dietary guidelines we should follow as to the protection of the kidney.

In terms of keeping kidney healthy, we should first pay attention to nourishing essence, which emphasis on solid essence and preventing its loss. In order to achieve such a goal, you can eat more food that contain tonic substance, we often call them “black food” like black beans, black rice, black sesame seed, walnut, etc., and of course some Chinese medicinal food is also a good choice. What also important is to catch the best time to protect your kidney.
We all know that protecting kidney should start from the scratch, and habits in the daily life are rich in varying kinds of common sense for protecting kidney. Such as the daily drinking, we should drink water not wit until we are very thirsty and should get into the habit of drinking all the time. Water quantity deficiency can lead to shortage of the body, serious deficiency may even cause dehydration, and of course this is a risk for kidney or even the whole body. In addition, limiting salt intake strictly is also helpful to protect kidney. Because excessive salt intake can increase the kidney burden or cause too much salt accumulating in the body which all damages to kidney.
We should also prevent excessive intake of purines, eat less food contain high purine as far as possible, such as meat, aquatic products, yeast powder, wine and chicken powder,etc. Because too much purine intake can cause uric acid in the body elevating.
If you want to know more about the diet that can help you keep healthy, you can consult with our specialists online.

Read more about: Reversing Renal Failure by Natural Treatment

Can patients with chronic nephritis be pregnant

Chronic nephritis is also called chronic glomerular nephritis,its clinical manifestations are proteinuria,edema and high blood pressure. It has longer duration and merging pregnancy are not uncommon.pregnancy can increase the burden of kidney and accordingly cause the symptoms mentioned above.

According to the varying degrees of nephritis, it also has different effects on the development of fetus. For patients have both chronic nephritis and high blood pressure often accompanied by placental function decline and insufficient supply of fetal blood. So people of this group should not be pregnant, because about 75% of these people will be complicated by severe pih high blood syndrome and stillbirth rate is extremely high.
Besides, patients whose renal function does not restore normal together with protein quantity, blood urea nitrogen and creatinine increasing, need to prevent renal failure appear. Thus patients are also not suitable to be pregnant. They should take induced abortion if it is early pregnancy.
However, if the chronic nephritis patients has basically normal renal function as well as only a small amount of urine protein and has a period of stability, then they can be pregnant, but should have a good rest and compensate enough nutrition like food contain high quality protein and vitamin. In addition, increasing the body resistance and avoiding all kinds of infections also do good for the recovery.
Clinical experience has proved that pregnant can aggravate the progression of nephritis and shorten the life span of patients.
If you want to learn more about chronic nephropathy, you can also ask our specialists online, they will give you satisfying answers.

Read more about: How long can I live with nephropyelitis

Modern medical treatment of IGA nephropathy

IGA nephropathy is the most common primary chronic glomerular disease, and its clinical manifestations are mainly protein urine or blood urine accompanied with protein urine. Here i will introduce some modern medical treatments of IGA nephropathy.

1. Adjust living habits. Especially in allusion to the individuals who have bad living habits, they should particularly change their bad habits and try their best to form new good living habits. Such as losing weight, giving up smoking, low-salt and low-fat diet, taking some aerobic exercise, etc.
2. Prevent infections. The best way to prevent infections is to boost resistance and avoid catching cold. If someone once get infected, he must get it controlled actively and thoroughly. If patients also have recurrent tonsillitis or certain blood urine concerned with tonsil infection, removing of the tonsils is suggested. Retrospective studies suggest that the tonsil excision is good for patients with mild-to-moderate IGA nephropathy.
3. Prevent drug use of ischemic and renal toxicity. The main measure is to ensure sufficient supply of blood so that we can avoid dehydration and severe hypotension. Reducing the use of renal toxicity drugs to maintain enough urine output is also helpful.
4. Other support therapy. Including the anticoagulation and antiplatelet aggregation, regulating blood lipid, traditional Chinese medicine, etc.
According to the above factors, we can conclude that the modern medical treatments of IGA nephropathy are some good living habits in the daily life. If you want to know more about IGA nephropathy and its treatments, you can contact our specialists online to acquire more information.

Read more about: How Does TCM Work in IgA Nephropathy(Autoimmune Disease) Treatment

What are the differences between lupus and ordinary skin disease?

Lupus is a disease that has a high morbidity and its damage to human body usually firstly embodies in the surface of the skin. So many people mistake lupus as ordinary skin disease and see the doctors in dermatological department.

In the first, skin disease is due to internal and external factors which can lead to changes of its morphology, structure and function, finally it will produce pathological process and varying kinds of clinical manifestations. While systemic lupus erythematosus is a systemic immune disease with multiple damages and a variety of autoantibodies, besides erythema on the skin, it also has the symptoms of low fever, renal involvement, photoresponse and pain in the joints of the limbs.
In the second place, patient’s skin with erythema mainly spread in the shape of butterfly, while ordinary skin disease have different manifestations depend on different categories. For example, damage to the skin of urticaria patients is mainly caused by allergy, and together with red rash that will disappear after allergic reaction fade out. On the other hand, the rash caused by lupus has dark color and will not disappear easily.
In the last, treatments are different between ordinary skin disease and lupus: ordinary skin disease can be treated by topical creams and some oral drugs, while hormonotherapy and immunotherapy is needed to treat lupus. What’s worse, there is no good way to prevent this kind of disease except to protest it by daily tonic.
Above all, if you find any symptoms related to lupus, you should attach great importance on it and take treatments as soon as possible. You can also ask our specialists online to learn about more information.

Read more about: Lupus Nephritis Cause &Symptom &Diagnosis

How does hyperuricemia cause damage to kidneys

Hyperuricemia and gout are two different names for one disease. Gout is a disease caused by a group of purine metabolic disorders, in clinic, it is characterized by hyperuricemia and some complications which is due to hyperuricemia, like the relapse of acute gout arthritis, tophus deposit and chronic arthritis or joint deformity due to tophus, all of which often do harm to kidneys and lead to chronic interstitial nephritis and uric acid stone.

Almost one third of the patients who have long-term gout have kidney damage and it is characterized by the following three forms:
1. Gouty nephropathy. Urate crystal deposition in the kidney tissues can cause interstitial nephritis, simply in the form of proteinuria and microscopic hematuria in the early stage, so it is easy to be ignored. However, with the progression of disease, proteinuria become sustainable. The impairment of concentrating function in kidney lead to a serious of phenomena such as nocturia increasing and low proportion of urine. Eventually, patients will convert to uremia from chronic azotemia.
2. Acute renal failure. This is because large amounts of uric acid crystals widely block the cavity of renal tubular, thus causing obstruction of urine stream .
3. Lithangiuria. About 20%-25% of primary gout patients have the complications of urinary stones related to high uric acid, part of the patients have kidney stone that occurs earlier than arthritis. While patients with secondary hyperuricemia have higher incidence in allusion to lithangiuria. Kidney stones like fine sediment can be excreted in the urine without any symptoms, but patients with larger stones often have renal colic, hematuresis and urinary tract infections.

With regard to the nursing of hyperuricemia, patients should attach great importance to develop good habits in the daily life.
Read more about: Why does renal failure patient experiences hematemesis

Why a lot of glomerular nephritis patients can be “asymptomatic”

Chronic glomerular nephritis patients be “asymptomatic” for a long term is associated with many factors. Here are some situations concerned.

1. Chronic nephritis is very easy to be ignored, because each kidney is composed of more than 10 million renal units and each nephron has strong ability to work. Each nephron can complete the workload which usually be done by 3~4 nephrons, so symptoms will appear only when the glomerular has been damaged more than half. What’s more, nephrons is non -renewable, once damaged, it will less and less as time goes by. The deterioration of renal function will have imperceptible development long before the clinical symptoms appear. However, when patients consider to see a doctor, the disease has developed into very serious stage.
2. Patients do not know the knowledge of kidney disease very well. Many patients in kidney disease know less or nothing about kidney disease. What’s worse, the symptoms of kidney disease, which are just lumbar acid, fatigue, edema, etc., are not very specific, so it’s easy to be ignored. Some other people don’t pay high attention to these symptoms, they just think these symptoms are just caused by fatigue, and if they rest for a period of time they will be fine. Neither you neglect it casually, nor you didn't care for the disease, the condition of your disease will deteriorate slowly in an imperceptible way. Therefore, when the patients have obvious symptoms or they can’t recover after a rest , they come to see the doctor eventually , but the extent of the disease has been very serious.
3. Early diagnosis lack sensitive index. Now all the renal function checks have some limitations, especially the diagnosis of the early nephropathy. This is because noninvasive examination isn't sensitive enough, while invasive examination is risky, so patients are often reluctant to accept it.
Above all, patients should pay special attention to every change in the body and take treatments as soon as possible.

Read more about：What symptoms can lead to nephritis?

Why serum creatinine often can’t accurately reflect renal function

Serum creatinine is a breakdown product of creatinine phosphate in muscle, most of which are endogenous and a small part of them are from food.

Our body produce creatinine at a fairly constant rate related to muscle mass. Serum creatinine in the body of someone who is tall and young and with larger muscle tissue volume is often supposed to be higher than the small and old one. Serum creatinine is filtered through glomerulus and only little is absorbed by kidney tubules which can also excrete. When the rate of glomerular filtration decline, the output of creatinine discharged by renal tubular plays a main part of the total discharged creatinine, leading to high evaluation level of GFR.
Since there are correlations between creatinine clearance rate and serum creatinine, the level of serum creatinine will not beyond normal range, especially among patients with smaller muscle mass, unless the glomerulus filtration rate decline substantially. When renal function has been impaired by 50%-70%(compensation stage),creatinine clearance also decrease, while the serum creatinine keep the normal level.

When GFR is reduced to more than 50% of the normal rate, creatinine begins to rise rapidly, so it is not sensitive to reflect the renal function. In addition, serum creatinine will lead to pseudo rise, if you eat meat, coffee, tea, exogenous sources of creatinine, take vigorous exercise which can increases muscle metabolism, and take drugs which are discharged by the channels of glomerular ion .The level of serum creatinine will have bigger changes with regards to different muscle mass, different gender, age, etc. Therefore, serum creatinine cannot often reflect the renal function accurately.
Read more about: Does high creatinine cause rashes

Is swelling sure to be kidney disease?

A great deal of factors can cause swelling, including physiologic and pathologic. In most cases, swelling is caused by kidney disease or heart disease. However, sometimes it also can be caused by liverish ascites, nutritional disorder due to protein deficiency or abnormal hormone results from climacteric disorder.

Next i will list some cases in which we can confirm someone’s swelling is caused by kidney disease. Generally speaking, patients at an early stage only experience slight eyelids swelling and without the leg edema, we call it recessive edema. Light edema on legs will usually be alleviated or disappear after patients taking a good rest, while the severe case will occur on lower limbs and ankles, and this situation is likely to cause swelling all over the body. In addition, edema caused by nephritis usually occur when patients have the symptom of oliguria and especially on eyelids as well as lower extremities, once appeared, difficult to fade.
Above all, swelling is a common manifestation of kidney disease, it is easily ignored unintentionally because of its similarity to some other disease. However, it is because of such characteristics of swelling that we should pay more attention to it and take appropriate treatment as soon as possible. Only in this way can we better protect our kidney and maintain a healthy state.
If you want to know more information about swelling caused by kidney disease or no matter what problems about kidney disease, you can consult us online which is just on your right hand side.
Read more about: How the edema related to chronic kidney disease

What Should We Do When We Found Ourselves Have Certain Kidney Disease

Usually, people will become nervous and anxiety when they got some disease. However, worrying can help you nothing but increase your bad mood. After being diagnosed with kidney disease, patients should calm down first and persuade self to face the reality.

First, patients need to realize that kidney disease is not always deadly but a common disease many people may come cross. Since disease is inevitable, what we can do is to take appropriate treatments actively. Having disease is not the most terrible thing, witnessing disease deteriorating day by day is.
Besides, patients with kidney disease are supposed to apart from everything that cause the disease they are suffering from, because a great deal of causes can induce kidney disease and different measures should be taken to prevent kidney disease from deteriorating. Diet, living habits and exercise frequency or intensity are all important factors patients should pay attention to.
Above all, seeing a doctor is essential to each patient with kidney disease, especially for those who have reached an advanced stage. Choosing a professional hospital with first-class service and favorable environment can provide a guarantee for your recovery to a large extent.

If you are interested in our hospital (Beijing United-tech nephrology Specialist Hospital) and our treatments (5C International Renal Health Restoring) about kidney disease, you can have a further conversation with our customer services online.
Read more about: 5C International Renal Restoring

How Much Will Patients Generally Spend to Treat Kidney Disease?

Kidney disease is a big conception which can be divided into varying kinds of specific categories, and each different kind of it is accompanied by different manifestations and appeared in different extent. Therefore, the expense of kidney disease ranges in large scope.

Generally speaking, you discover kidney disease early, then you will spend less money than later. It will help you save money if you take treatments when disease just occur, and you should also have patience to insist on. However, no matter what kind of kidney disease it is, it is supposed to be attached great importance to, and its expenditure is pretty expensive.. Especially for those patients who need to do dialysis or kidney transplanting, they confront expensive cost as well as the threat to life.
If you want to maintain a healthy state while cost less money, what you need to do is to prevent disease as soon as possible, check-up regularly, develop good living habits. Thus we resist disease starting from every details in the daily life, such as light diet, appropriate exercise and keep a happy mood. When you prevent kidney disease from getting worse you can save your costs uttermost.

If you want to know more about the treatments of kidney disease and its cost, you can leave messages to our customer service online.
Read more about: Treatments for Kidney Lesions

Clinical manifestations of chronic glomerular nephritis syndrome

Chronic glomerulonephritis(chronic nephritis) syndrome refers to a group of similar clinical manifestations which have diverse etiology and different pathological form.

It is important to learn about the clinical manifestations of chronic nephritis because of its hidden causes and mild symptoms that are easily to be overlooked at the early stage. Next i will list some common symptoms summarized by senior experts from Beijing United-Tech Nephrology Specialist Hospital.
1. Edema. In the whole course of the disease, most patients will appear to have different degree of edema, and many patients start with edema. Patients with mild edema only show edema on eyelid, faces after getting up in the morning, but it can subside after a few hours. But if you want to tell it from the edema caused by lack of sleep or staying up late, you should do a urine test to make sure whether it is nephritis.
2. Hypertension. Some patients go to see doctor because of hypertension, and urine test is the only necessary means to find out nephritis. For patients with chronic nephritis, hypertension will occur sooner or later. The increasing of blood pressure can be either persistent or intermittent, and it usually implies that the lesions have reached a certain degree. What’s more, the degree of blood pressure is closely associated with prognosis, generally the higher your blood pressure is, the longer it lasts, the more dangerous you will be and the worse of the prognosis.
3. The abnormal urine test. Chronic kidney disease patients’urine test will be surely abnormal, including the abnormally reasonable amount of urine and abnormal microscopic examination.The urine volume of the patients with edema will be reduced, and the more serious of the edema,the more urine he will reduced.Generally, if the patients do not have edema, his urine volume will be normal
4. Renal insufficiency. Chronic nephritis patients will have the symptoms of dizziness, insomnia and mental fatigue. Moreover, when patients’ renal function decreases, they will feel less of appetite, fatigue resistance, different degrees of anemia and other symptoms.

Above symptoms can either come together or alone, if patients can not have them under control, they are very likely to develop renal failure or even uremia. So patients should pay more attention to symptoms in the daily life.
Read more about What symptoms can lead to nephritis?